ID AMPDB_7 PN Guanylate-binding protein 6 PF Guanylate-binding protein 6 GN Gbp6 Mpa2l SO Mus musculus (Mouse) PL 611 PE Evidence at transcript level XX AC 'A': 39, 'R': 24, 'N': 27, 'D': 33, 'C': 10, 'Q': 41, 'E': 60, 'G': 22, 'H': 15, 'I': 31, AC 'L': 66, 'K': 56, 'M': 18, 'F': 29, 'P': 20, 'S': 33, 'T': 31, 'W': 5, 'Y': 15, 'V': 36 AF 'A': 6.38%, 'R': 3.93%, 'N': 4.42%, 'D': 5.4%, 'C': 1.64%, 'Q': 6.71%, 'E': 9.82%, 'G': 3.6%, 'H': 2.45%, 'I': 5.07%, AF 'L': 10.8%, 'K': 9.17%, 'M': 2.95%, 'F': 4.75%, 'P': 3.27%, 'S': 5.4%, 'T': 5.07%, 'W': 0.82%, 'Y': 2.45%, 'V': 5.89% MA MO L LO W BA 266 LA 345 AA 95 BC 93 MC 0 MF 0 XX MM 70442.702 AI 85.385 II 41.908 HP -0.489 HM 0.703 IP 5.927 C7 -12.166 SF 0.298, 0.167, 0.3 [Helix, Turn, Sheet] AR 0.08 ME 49850, 50475 XX TO Listeria monocytogenes (Gram-positive) TO Mycobacterium bovis (Gram-positive) TO Toxoplasma gondii AM Antimicrobial AM Anti-listeria AM Anti-protozoal AM Anti-gram-Positive EA Hydrolase IE Not found OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 19468303 XR PubMed: 15489334 XR PubMed: 18025219 XR PubMed: 21551061 XR UniProt: A0A0G2JDV3 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: A0A0G2JDV3 XR GemBank;EMBL: AK128993 XR GemBank;EMBL: GL456119 XR GemBank;EMBL: BC057969 XR GemBank;EMBL: BC115768 XR GemBank;EMBL: BK005759 XR CCDS: CCDS19492.1 XR RefSeq: NP_919317.2 XR RefSeq: XP_006534750.1 XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR030386 XR InterPro: IPR037684 XR InterPro: IPR003191 XR InterPro: IPR036543 XR InterPro: IPR015894 XR InterPro: IPR027417 XR PANTHER: XR PROSITE: PS51715 XR Ensembl: XR KEGG: mmu:100702 XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: A0A0G2JDV3 SQ SEQUENCE 70442.702 DA MW 611AA MTQPQMAPIC LVENHNEQLS VNQEAIEILD KISQPVVVVA IVGLYRTGKS YLMNCLAGQN HGFPLGSTVQ SQTKGIWMWC MPHPTKPEHT LVLLDTEGLG DVEKGDPKND LWIFALSVLL SSTFIYNSMI TINHQALEQL QYVTELTELI RAKSSPNPAG IKNSTEFVSF FPDFVWTVRD FMLELKLNGE DITSDDYLEN ALKLIPGDKP RMQASNSCRE CIRLFFPNRK CFVFDRPTHD KELLQKLDSI TEDQLDPKFQ EVTKAFVSYI FTYAKIKTLK EGIKVTGNRL GILVTTYVNA INSGAVPCLD DAVTTLAQRE NSVAVQKAAD HYSEQMAQRL RLPTETLQEL LDVHAACEKE AMAVFMEHSF KDENQQFLKK LVELIGENKE LFLSKNEEAS NKYCQEELDR LSKDFMENIS TFFVPCGHKL YMDKREKIEH DYWQVPRKGV KASEVFQSFL QSQAFIESSI LQADTALTAG EKAIAEERAQ KVAAEKEQEL LRQKQKEQQE YMEAQEKSHK ENLEQLRRKL EQEREQDIKD HDMMLKKLMK DQKAFLEEGF KKKAEEMNKE IQQLRDVIKD KKRNTDRIKE ALLNGFSTVL FHYLVRYLKH L // ID AMPDB_14 PN Figainin 2 PF Figainin 2 GN Not found SO Boana raniceps (Chaco tree frog) (Hyla roeschmanni) PL 84 PE Evidence at protein level XX AC 'A': 5, 'R': 3, 'N': 3, 'D': 1, 'C': 1, 'Q': 1, 'E': 18, 'G': 6, 'H': 2, 'I': 3, AC 'L': 10, 'K': 12, 'M': 2, 'F': 5, 'P': 2, 'S': 3, 'T': 2, 'W': 0, 'Y': 0, 'V': 5 AF 'A': 5.95%, 'R': 3.57%, 'N': 3.57%, 'D': 1.19%, 'C': 1.19%, 'Q': 1.19%, 'E': 21.43%, 'G': 7.14%, 'H': 2.38%, 'I': 3.57%, AF 'L': 11.9%, 'K': 14.29%, 'M': 2.38%, 'F': 5.95%, 'P': 2.38%, 'S': 3.57%, 'T': 2.38%, 'W': 0%, 'Y': 0%, 'V': 5.95% MA W, Y MO E LO C, D, Q BA 38 LA 46 AA 17 BC 19 MC 0 MF 0 XX MM 9632.085 AI 83.571 II 54.173 HP -0.652 HM 0.661 IP 5.014 C7 -3.853 SF 0.274, 0.167, 0.417 [Helix, Turn, Sheet] AR 0.06 ME 0, 0 XX TO Dengue TO E.casseliflavus (Gram-positive) TO E.coli (Gram-negative) TO E.faecalis (Gram-positive) TO K.pneumoniae (Gram-negative) TO P.aeruginosa (Gram-negative) TO S.aureus (Gram-positive) TO S.epidermidis (Gram-positive) TO T.cruzi TO Yellow Fever AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Antiviral protein AM Anti-candida AM Anti-protozoal AM Anti-gram-negative AM Anti-gram-Positive EA Not found IE Not found OE Cytolysis OE Anti-cancer OE Cytolytic OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 32443921 XR UniProt: A0A2L2DDD0 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: A0A2L2DDD0 XR Genbank;EMBL: KY748199 XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR004275 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 9632.085 DA MW 84AA MAFLKKSLFL VLFLGIVSLS VCEEEKREGE EKEEKREEEE GKEENEDGNE EHKEKRFLGA ILKIGHALAK TVLPMVTNAF KPKQ // ID AMPDB_15 PN Figainin 1 PF Figainin 1 GN Not found SO Boana raniceps (Chaco tree frog) (Hyla roeschmanni) PL 68 PE Evidence at protein level XX AC 'A': 5, 'R': 2, 'N': 4, 'D': 0, 'C': 0, 'Q': 1, 'E': 13, 'G': 6, 'H': 0, 'I': 3, AC 'L': 12, 'K': 8, 'M': 1, 'F': 5, 'P': 1, 'S': 3, 'T': 2, 'W': 0, 'Y': 0, 'V': 2 AF 'A': 7.35%, 'R': 2.94%, 'N': 5.88%, 'D': 0%, 'C': 0%, 'Q': 1.47%, 'E': 19.12%, 'G': 8.82%, 'H': 0%, 'I': 4.41%, AF 'L': 17.65%, 'K': 11.76%, 'M': 1.47%, 'F': 7.35%, 'P': 1.47%, 'S': 4.41%, 'T': 2.94%, 'W': 0%, 'Y': 0%, 'V': 2.94% MA C, D, H, W, Y MO E LO M, P, Q BA 35 LA 33 AA 10 BC 13 MC 0 MF 0 XX MM 7639.829 AI 101.912 II 48.787 HP -0.274 HM 0.53 IP 4.639 C7 -2.981 SF 0.324, 0.206, 0.456 [Helix, Turn, Sheet] AR 0.074 ME 0, 0 XX TO E.casseliflavus (Gram-positive) TO E.coli (Gram-negative) TO E.faecalis (Gram-positive) TO K.pneumoniae (Gram-negative) TO S.aureus (Gram-positive) TO S.epidermidis (Gram-positive) TO T.cruzi AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Anti-candida AM Anti-protozoal AM Anti-gram-negative AM Anti-gram-Positive EA Not found IE Not found OE Cytolysis OE Anti-cancer OE Cytolytic OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 32967114 XR UniProt: A0A2L2DDE6 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: A0A2L2DDE6 XR Genbank;EMBL: KY748198 XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR004275 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 7639.829 DA MW 68AA MAFLKKSLFL VLFLGLVSLS IGEEEKREEE EKNEEGANQE ENAENKEKRF IGTLIPLALG ALTKLFKG // ID AMPDB_146 PN L-amino-acid oxidase BjussuLAAO-II PF L-amino-acid oxidase BjussuLAAO-II GN Not found SO Bothrops jararacussu (Jararacussu) PL 116 PE Evidence at protein level XX AC 'A': 5, 'R': 5, 'N': 7, 'D': 11, 'C': 1, 'Q': 2, 'E': 16, 'G': 7, 'H': 1, 'I': 4, AC 'L': 7, 'K': 8, 'M': 2, 'F': 7, 'P': 10, 'S': 4, 'T': 5, 'W': 2, 'Y': 6, 'V': 6 AF 'A': 4.31%, 'R': 4.31%, 'N': 6.03%, 'D': 9.48%, 'C': 0.86%, 'Q': 1.72%, 'E': 13.79%, 'G': 6.03%, 'H': 0.86%, 'I': 3.45%, AF 'L': 6.03%, 'K': 6.9%, 'M': 1.72%, 'F': 6.03%, 'P': 8.62%, 'S': 3.45%, 'T': 4.31%, 'W': 1.72%, 'Y': 5.17%, 'V': 5.17% MA MO E LO C, H BA 50 LA 66 AA 14 BC 27 MC 0 MF 0 XX MM 13514.851 AI 56.293 II 36.658 HP -0.977 HM 0.61 IP 4.068 C7 -13.947 SF 0.276, 0.241, 0.259 [Helix, Turn, Sheet] AR 0.129 ME 19940, 19940 XX TO Leishmania amazonensis TO Trypanosoma cruzi AM Antibiotic AM Antimicrobial AM Anti-protozoal EA Oxidoreductase IE Not found OE Cytolysis OE Toxin OE Cytotoxin OE Hemolytic OE Non-ribosomal XX XR PubMed: 28495622 XR PubMed: 29222016 XR PubMed: 30534149 XR PubMed: 30654040 XR UniProt: P0DV78 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P0DV78 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 13514.851 DA MW 116AA ADDRNPLEEC FRETDYEEFL EIARNGLSDT DNPKEGWYAN LGPMRLNEFS QENENAWYFI KDPGVLDYPV KPSEVGKHDD IFAYEKRFDE IVGGMDKEVT VTYQTSEKFE PPLPPK // ID AMPDB_197 PN Dermaseptin-B2 PF Dermaseptin-B2 GN ADR SO Phyllomedusa bicolor (Two-colored leaf frog) (Rana bicolor) PL 81 PE Evidence at protein level XX AC 'A': 12, 'R': 2, 'N': 1, 'D': 3, 'C': 1, 'Q': 3, 'E': 15, 'G': 6, 'H': 0, 'I': 2, AC 'L': 9, 'K': 10, 'M': 2, 'F': 3, 'P': 0, 'S': 6, 'T': 0, 'W': 1, 'Y': 0, 'V': 5 AF 'A': 14.81%, 'R': 2.47%, 'N': 1.23%, 'D': 3.7%, 'C': 1.23%, 'Q': 3.7%, 'E': 18.52%, 'G': 7.41%, 'H': 0%, 'I': 2.47%, AF 'L': 11.11%, 'K': 12.35%, 'M': 2.47%, 'F': 3.7%, 'P': 0%, 'S': 7.41%, 'T': 0%, 'W': 1.23%, 'Y': 0%, 'V': 6.17% MA H, P, T, Y MO E LO C, N, W BA 40 LA 41 AA 12 BC 18 MC 0 MF 0 XX MM 8844.035 AI 85.679 II 52.554 HP -0.402 HM 0.678 IP 4.385 C7 -6.039 SF 0.247, 0.16, 0.469 [Helix, Turn, Sheet] AR 0.049 ME 5500, 5500 XX TO Gram Negative Bacteria and Gram Positive Bacteria AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Fungicide AM Anti-protozoal AM Anti-gram-negative AM Anti-gram-Positive EA Not found IE Not found OE Cytotoxin OE Hemolytic OE Synergistic peptide OE Non-ribosomal XX XR PubMed: 8466537 XR PubMed: 1438301 XR PubMed: 7842473 XR PubMed: 8306981 XR PubMed: 8565049 XR PubMed: 12709067 XR PubMed: 15766883 XR PubMed: 16401077 XR PubMed: 18637027 XR PubMed: 18644413 XR PubMed: 19113844 XR UniProt: P31107 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P31107 XR Genbank;EMBL: X70278 XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR022731 XR InterPro: IPR004275 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 8844.035 DA MW 81AA MAFLKKSLFL VLFLGLVSLS ICEEEKRENE DEEEQEDDEQ SEMKRGLWSK IKEVGKEAAK AAAKAAGKAA LGAVSEAVGE Q // ID AMPDB_200 PN Guanylate-binding protein 2 PF Guanylate-binding protein 2 GN GBP2 SO Homo sapiens (Human) PL 591 PE Evidence at protein level XX AC 'A': 39, 'R': 21, 'N': 25, 'D': 34, 'C': 9, 'Q': 35, 'E': 57, 'G': 27, 'H': 9, 'I': 29, AC 'L': 67, 'K': 58, 'M': 17, 'F': 23, 'P': 24, 'S': 40, 'T': 24, 'W': 6, 'Y': 14, 'V': 33 AF 'A': 6.6%, 'R': 3.55%, 'N': 4.23%, 'D': 5.75%, 'C': 1.52%, 'Q': 5.92%, 'E': 9.64%, 'G': 4.57%, 'H': 1.52%, 'I': 4.91%, AF 'L': 11.34%, 'K': 9.81%, 'M': 2.88%, 'F': 3.89%, 'P': 4.06%, 'S': 6.77%, 'T': 4.06%, 'W': 1.02%, 'Y': 2.37%, 'V': 5.58% MA MO L LO W BA 265 LA 326 AA 88 BC 91 MC 0 MF 0 XX MM 67209.018 AI 86.142 II 40.524 HP -0.485 HM 0.702 IP 5.411 C7 -11.654 SF 0.291, 0.196, 0.305 [Helix, Turn, Sheet] AR 0.073 ME 53860, 54360 XX TO Toxoplasma gondii AM Antimicrobial AM Anti-protozoal EA Hydrolase IE Not found OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 1715024 XR PubMed: 17974005 XR PubMed: 14702039 XR PubMed: 16710414 XR PubMed: 15489334 XR PubMed: 8706832 XR PubMed: 17266443 XR PubMed: 21151871 XR UniProt: P32456 XR AlphaFoldDB: P32456 XR GemBank;EMBL: M55543 XR GemBank;EMBL: AL832451 XR GemBank;EMBL: AK314325 XR GemBank;EMBL: CR457062 XR GemBank;EMBL: AC104459 XR GemBank;EMBL: CH471097 XR GemBank;EMBL: BC073163 XR CCDS: CCDS719.1 XR RefSeq: NP_004111.2 XR STRING: 9606.ENSP00000359497 XR IntAct: P32456 XR MINT: P32456 XR DIP: XR BioGRID: 108904 XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR030386 XR InterPro: IPR037684 XR InterPro: IPR003191 XR InterPro: IPR036543 XR InterPro: IPR015894 XR InterPro: IPR027417 XR PANTHER: XR PROSITE: PS51715 XR Ensembl: ENSGT00940000162297 XR KEGG: hsa:2634 XR GeneTree: ENSGT00940000162297 XR BRENDA: XR BioCyc: XR RNAct: P32456 SQ SEQUENCE 67209.018 DA MW 591AA MAPEINLPGP MSLIDNTKGQ LVVNPEALKI LSAITQPVVV VAIVGLYRTG KSYLMNKLAG KKNGFSLGST VKSHTKGIWM WCVPHPKKPE HTLVLLDTEG LGDIEKGDNE NDSWIFALAI LLSSTFVYNS MGTINQQAMD QLHYVTELTD RIKANSSPGN NSVDDSADFV SFFPAFVWTL RDFTLELEVD GEPITADDYL ELSLKLRKGT DKKSKSFNDP RLCIRKFFPK RKCFVFDWPA PKKYLAHLEQ LKEEELNPDF IEQVAEFCSY ILSHSNVKTL SGGIPVNGPR LESLVLTYVN AISSGDLPCM ENAVLALAQI ENSAAVEKAI AHYEQQMGQK VQLPTETLQE LLDLHRDSER EAIEVFMKNS FKDVDQMFQR KLGAQLEARR DDFCKQNSKA SSDCCMALLQ DIFGPLEEDV KQGTFSKPGG YRLFTQKLQE LKNKYYQVPR KGIQAKEVLK KYLESKEDVA DALLQTDQSL SEKEKAIEVE RIKAESAEAA KKMLEEIQKK NEEMMEQKEK SYQEHVKQLT EKMERDRAQL MAEQEKTLAL KLQEQERLLK EGFENESKRL QKDIWDIQMR SKSLEPICNI L // ID AMPDB_249 PN Defensin MGD-1 PF Defensin MGD-1 GN FH3 SO Mytilus galloprovincialis (Mediterranean mussel) PL 60 PE Evidence at protein level XX AC 'A': 2, 'R': 8, 'N': 3, 'D': 5, 'C': 8, 'Q': 1, 'E': 3, 'G': 9, 'H': 3, 'I': 3, AC 'L': 1, 'K': 1, 'M': 0, 'F': 4, 'P': 2, 'S': 1, 'T': 1, 'W': 1, 'Y': 3, 'V': 1 AF 'A': 3.33%, 'R': 13.33%, 'N': 5%, 'D': 8.33%, 'C': 13.33%, 'Q': 1.67%, 'E': 5%, 'G': 15%, 'H': 5%, 'I': 5%, AF 'L': 1.67%, 'K': 1.67%, 'M': 0%, 'F': 6.67%, 'P': 3.33%, 'S': 1.67%, 'T': 1.67%, 'W': 1.67%, 'Y': 5%, 'V': 1.67% MA M MO G LO K, L, Q, S, T, V, W BA 23 LA 37 AA 12 BC 8 MC 0 MF 0 XX MM 6919.714 AI 34.167 II 53.942 HP -0.805 HM 0.58 IP 7.686 C7 0.78 SF 0.217, 0.25, 0.1 [Helix, Turn, Sheet] AR 0.133 ME 9970, 10470 XX TO No Target Organism Found AM Antibiotic AM Antimicrobial AM Defensin AM Anti-protozoal EA Not found IE Not found OE Cytotoxin OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 10564642 XR PubMed: 8925841 XR PubMed: 11087396 XR UniProt: P80571 XR AlphaFoldDB: P80571 XR Genbank;EMBL: AF162337 XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR001542 XR InterPro: IPR036574 XR PANTHER: XR PROSITE: PS51378 XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 6919.714 DA MW 60AA GFGCPNNYQC HRHCKSIPGR CGGYCGGWHR LRCTCYRCGG RREDVEDIFD IFDNEAADRF // ID AMPDB_294 PN Guanylate-binding protein 1 PF Guanylate-binding protein 1 GN Gbp1 Gbp-1 Mag-1 Mpa1 SO Mus musculus (Mouse) PL 589 PE Evidence at protein level XX AC 'A': 35, 'R': 23, 'N': 21, 'D': 26, 'C': 10, 'Q': 44, 'E': 62, 'G': 27, 'H': 10, 'I': 32, AC 'L': 64, 'K': 50, 'M': 23, 'F': 26, 'P': 18, 'S': 37, 'T': 32, 'W': 5, 'Y': 16, 'V': 28 AF 'A': 5.94%, 'R': 3.9%, 'N': 3.57%, 'D': 4.41%, 'C': 1.7%, 'Q': 7.47%, 'E': 10.53%, 'G': 4.58%, 'H': 1.7%, 'I': 5.43%, AF 'L': 10.87%, 'K': 8.49%, 'M': 3.9%, 'F': 4.41%, 'P': 3.06%, 'S': 6.28%, 'T': 5.43%, 'W': 0.85%, 'Y': 2.72%, 'V': 4.75% MA MO L LO W BA 258 LA 331 AA 83 BC 88 MC 0 MF 0 XX MM 67711.662 AI 83.294 II 46.616 HP -0.465 HM 0.625 IP 5.226 C7 -14.619 SF 0.29, 0.175, 0.312 [Helix, Turn, Sheet] AR 0.08 ME 51340, 51965 XX TO Listeria monocytogenes (Gram-positive) TO Mycobacterium bovis (Gram-positive) TO Toxoplasma gondii AM Antimicrobial AM Anti-listeria AM Anti-protozoal AM Anti-gram-Positive EA Hydrolase IE Not found OE Cell membrane OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 1753106 XR PubMed: 1715024 XR PubMed: 15489334 XR PubMed: 10888661 XR PubMed: 18025219 XR PubMed: 21183079 XR PubMed: 21551061 XR UniProt: Q01514 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: Q01514 XR Genbank;EMBL: M63961 XR Genbank;EMBL: M55544 XR Genbank;EMBL: BC108990 XR CCDS: CCDS38658.1 XR RefSeq: XR STRING: 10090.ENSMUSP00000029936 XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR030386 XR InterPro: IPR037684 XR InterPro: IPR003191 XR InterPro: IPR036543 XR InterPro: IPR015894 XR InterPro: IPR027417 XR PANTHER: XR PROSITE: PS51715 XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: Q01514 SQ SEQUENCE 67711.662 DA MW 589AA MASEIHMSEP MCLIENTEAQ LVINQEALRI LSAITQPVVV VAIVGLYRTG KSYLMNKLAG KRTGFSLGST VQSHTKGIWM WCVPHPKKAG QTLVLLDTEG LEDVEKGDNQ NDCWIFALAV LLSSTFIYNS IGTINQQAMD QLHYVTELTD LIKSKSSPDQ SDVDNSANFV GFFPIFVWTL RDFSLDLEFD GESITPDEYL ETSLALRKGT DENTKKFNMP RLCIRKFFPK RKCFIFDRPG DRKQLSKLEW IQEDQLNKEF VEQVAEFTSY IFSYSGVKTL SGGITVNGPR LKSLVQTYVS AICSGELPCM ENAVLTLAQI ENSAAVQKAI TYYEEQMNQK IHMPTETLQE LLDLHRTCER EAIEVFMKNS FKDVDQKFQE ELGAQLEAKR DAFVKKNMDM SSAHCSDLLE GLFAHLEEEV KQGTFYKPGG YYLFLQRKQE LEKKYIQTPG KGLQAEVMLR KYFESKEDLA DTLLKMDQSL TEKEKQIEME RIKAEAAEAA NRALAEMQKK HEMLMEQKEQ SYQEHMKQLT EKMEQERKEL MAEQQRIISL KLQEQERLLK QGFQNESLQL RQEIEKIKNM PPPRSCTIL // ID AMPDB_341 PN Guanylate-binding protein 1 PF Guanylate-binding protein 1 GN Gbp2 SO Rattus norvegicus (Rat) PL 589 PE Evidence at protein level XX AC 'A': 36, 'R': 22, 'N': 22, 'D': 23, 'C': 10, 'Q': 35, 'E': 66, 'G': 29, 'H': 10, 'I': 35, AC 'L': 67, 'K': 54, 'M': 15, 'F': 27, 'P': 17, 'S': 40, 'T': 31, 'W': 4, 'Y': 14, 'V': 32 AF 'A': 6.11%, 'R': 3.74%, 'N': 3.74%, 'D': 3.9%, 'C': 1.7%, 'Q': 5.94%, 'E': 11.21%, 'G': 4.92%, 'H': 1.7%, 'I': 5.94%, AF 'L': 11.38%, 'K': 9.17%, 'M': 2.55%, 'F': 4.58%, 'P': 2.89%, 'S': 6.79%, 'T': 5.26%, 'W': 0.68%, 'Y': 2.38%, 'V': 5.43% MA MO L LO W BA 262 LA 327 AA 86 BC 89 MC 0 MF 0 XX MM 67109.047 AI 89.406 II 45.904 HP -0.385 HM 0.793 IP 5.413 C7 -12.613 SF 0.304, 0.183, 0.312 [Helix, Turn, Sheet] AR 0.076 ME 42860, 43485 XX TO Toxoplasma gondii AM Antimicrobial AM Anti-protozoal EA Hydrolase IE Not found OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 8148370 XR UniProt: Q63663 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: Q63663 XR Genbank;EMBL: M80367 XR CCDS: XR RefSeq: NP_598308.1 XR STRING: 10116.ENSRNOP00000061437 XR IntAct: XR MINT: XR DIP: XR BioGRID: 251165 XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR030386 XR InterPro: IPR037684 XR InterPro: IPR003191 XR InterPro: IPR036543 XR InterPro: IPR015894 XR InterPro: IPR027417 XR PANTHER: XR PROSITE: PS51715 XR Ensembl: XR KEGG: rno:171164 XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 67109.047 DA MW 589AA MASEIHMLQP MCLIENTEAH LVINQEALRI LSAINQPVVV VAIVGLYRTG KSYLMNKLAG KRTGFSLGST VQSHTKGIWM WCVPHPKKAG QTLVLLDTEG LEDVEKGDNQ NDCWIFALAV LLSSTFVYNS MGTINQQAMD QLHYVTELTD LIKSKSSPDQ SGIDDSANFV GFFPTFVWAL RDFSLELEVN GKLVTPDEYL EHSLTLKKGA DKKTKSFNEP RLCIRKFFPK RKCFIFDRPA LRKQLCKLET LGEEELCSEF VEQVAEFTSY IFSYSAVKTL SGGIIVNGPR LKSLVQTYVG AISSGSLPCM ESAVLTLAQI ENSAAVQKAI THYEEQMNQK IQMPTETLQE LLDLHRLIER EAIEIFLKNS FKDVDQKFQT ELGNLLISKR DAFIKKNSDV SSAHCSDLIE DIFGPLEEEV KQGTFSKPGG YFLFLQMRQE LEKKYNQAPG KGLEAEAVLK KYFESKEDIV ETLLKTDQSL TEAAKEIEVE RIKAETAEAA NRELAEKQEK FELMMQQKEE SYQEHVRQLT EKMKEEQKKL IEEQDNIIAL KLREQEKFLR EGYENESKKL LREIENMKRR QSPGKCTIL // ID AMPDB_373 PN Guanylate-binding protein 7 PF Guanylate-binding protein 7 GN GBP7 GBP4L SO Homo sapiens (Human) PL 638 PE Evidence at protein level XX AC 'A': 46, 'R': 25, 'N': 28, 'D': 25, 'C': 11, 'Q': 37, 'E': 68, 'G': 27, 'H': 14, 'I': 35, AC 'L': 68, 'K': 55, 'M': 19, 'F': 28, 'P': 23, 'S': 44, 'T': 28, 'W': 5, 'Y': 13, 'V': 39 AF 'A': 7.21%, 'R': 3.92%, 'N': 4.39%, 'D': 3.92%, 'C': 1.72%, 'Q': 5.8%, 'E': 10.66%, 'G': 4.23%, 'H': 2.19%, 'I': 5.49%, AF 'L': 10.66%, 'K': 8.62%, 'M': 2.98%, 'F': 4.39%, 'P': 3.61%, 'S': 6.9%, 'T': 4.39%, 'W': 0.78%, 'Y': 2.04%, 'V': 6.11% MA MO E; L LO W BA 290 LA 348 AA 94 BC 93 MC 0 MF 0 XX MM 72513.233 AI 87.9 II 46.482 HP -0.383 HM 0.747 IP 5.836 C7 -12.307 SF 0.295, 0.191, 0.315 [Helix, Turn, Sheet] AR 0.072 ME 46870, 47495 XX TO No Target Organism Found AM Antimicrobial AM Anti-listeria AM Anti-parasitic AM Anti-protozoal EA Hydrolase IE Not found OE Signal peptide OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 14702039 XR PubMed: 16710414 XR PubMed: 33408175 XR UniProt: Q8N8V2 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: Q8N8V2 XR Genbank;EMBL: AK096141 XR Genbank;EMBL: AC104459 XR CCDS: CCDS720.1 XR RefSeq: NP_997281.2 XR STRING: 9606.ENSP00000294671 XR IntAct: Q8N8V2 XR MINT: XR DIP: XR BioGRID: 132790 XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR030386 XR InterPro: IPR037684 XR InterPro: IPR003191 XR InterPro: IPR036543 XR InterPro: IPR015894 XR InterPro: IPR027417 XR PANTHER: XR PROSITE: PS51715 XR Ensembl: ENSGT00940000164365 XR KEGG: hsa:388646 XR GeneTree: ENSGT00940000164365 XR BRENDA: XR BioCyc: XR RNAct: Q8N8V2 SQ SEQUENCE 72513.233 DA MW 638AA MASEIHMPGP VCLTENTKGH LVVNSEALEI LSAITQPVVV VAIVGLYRTG KSYLMNKLAG KNKGFPLGCT VKSETKGIWM WCVPHPSKPN HTLILLDTEG LGDMEKSDPK SDSWIFALAV LLSSSFVYNS MGTINHQALE QLHYVTELTE LIRAKSCPRP DEVEDSSEFV SFFPDFIWTV RDFTLELKLD GHPITEDEYL ENALKLISGK NPQIQNSNKP REWIRHFFPK QKCFVFDRPI NDKKLLLHVE EVREDQLDSN FQMQSENFCS YIFTHAKTKT LREGILVTGN RLGMLVETYL DAINSGATPC LENAMAVLAQ CENSAAVQRA ANHYSQQMAQ QVRFPTDTLQ ELLDVHAVCE REAIAVFMEY SFKDKSQEFQ KKLVDTMEKK KEDFVLQNEE ASAKYCQAEL KRLSELLTES ISRGTFFVPG GHNIYLEAKK KIEQDYTLVP RKGVKADEVL QSFLQSQVVI EESILQSDKA LTAGEKAIAA KQAKKEAAEK EQELLRQKQK EQQQMMEAQE RSFQENIAQL KKKMEREREN YMRELRKMLS HKMKVLEELL TEGFKEIFES LNEEINRLKE QIEAAENEEP SVFSQILDVA GSIFIAALPG AAKLVDLGMK ILSSLCNRLR NPGKKIIS // ID AMPDB_383 PN Guanylate-binding protein 7 PF Guanylate-binding protein 7 GN Gbp7 Gbp4l SO Mus musculus (Mouse) PL 638 PE Evidence at protein level XX AC 'A': 40, 'R': 33, 'N': 30, 'D': 30, 'C': 9, 'Q': 40, 'E': 66, 'G': 28, 'H': 15, 'I': 30, AC 'L': 65, 'K': 53, 'M': 17, 'F': 25, 'P': 18, 'S': 46, 'T': 29, 'W': 4, 'Y': 12, 'V': 48 AF 'A': 6.27%, 'R': 5.17%, 'N': 4.7%, 'D': 4.7%, 'C': 1.41%, 'Q': 6.27%, 'E': 10.34%, 'G': 4.39%, 'H': 2.35%, 'I': 4.7%, AF 'L': 10.19%, 'K': 8.31%, 'M': 2.66%, 'F': 3.92%, 'P': 2.82%, 'S': 7.21%, 'T': 4.55%, 'W': 0.63%, 'Y': 1.88%, 'V': 7.52% MA MO E LO W BA 275 LA 363 AA 101 BC 96 MC 0 MF 0 XX MM 72720.931 AI 86.16 II 40.533 HP -0.502 HM 0.765 IP 6.265 C7 -9.092 SF 0.288, 0.191, 0.295 [Helix, Turn, Sheet] AR 0.064 ME 39880, 40380 XX TO Listeria monocytogenes (Gram-positive) TO Mycobacterium bovis (Gram-positive) TO T.gondii TO Toxoplasma gondii AM Antimicrobial AM Anti-listeria AM Anti-parasitic AM Anti-protozoal AM Anti-gram-Positive EA Hydrolase IE Not found OE Signal peptide OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 15449545 XR PubMed: 16141072 XR PubMed: 19468303 XR PubMed: 15489334 XR PubMed: 18025219 XR PubMed: 21183079 XR PubMed: 21551061 XR PubMed: 31689351 XR PubMed: 31964735 XR PubMed: 33408175 XR UniProt: Q91Z40 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: Q91Z40 XR GemBank;EMBL: AK087751 XR GemBank;EMBL: AK131176 XR GemBank;EMBL: AK036666 XR GemBank;EMBL: GL456099 XR GemBank;EMBL: BC010229 XR GemBank;EMBL: BK005760 XR CCDS: CCDS38657.1 XR RefSeq: NP_001076781.1 XR RefSeq: NP_663520.2 XR STRING: 10090.ENSMUSP00000049104 XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR030386 XR InterPro: IPR037684 XR InterPro: IPR003191 XR InterPro: IPR036543 XR InterPro: IPR015894 XR InterPro: IPR027417 XR PANTHER: XR PROSITE: PS51715 XR Ensembl: ENSGT00940000163522 XR KEGG: mmu:229900 XR GeneTree: ENSGT00940000163522 XR BRENDA: XR BioCyc: XR RNAct: Q91Z40 SQ SEQUENCE 72720.931 DA MW 638AA MASGPNMEAP VCLVENENEE LRVNSKAINI LERITQPVVV VAIVGLYRTG KSYLMNRLAG QNHGFNLGTT VRSETKGIWM WCVPHPSKPK FTLVLLDTEG LGDVEKGDPK NDSWIFALAV LLSSTFVYNS MSTINHQALE QLHYVTELTE RIRAKSTSRS EEVDDSDEFV SFFPDFIWTV RDFVLELKLE GRVITADEYL ENALKLIPGM SIKAQKANLP RECIRHFFPR RKCFVFDRPT KDKELLVHVE EMPEDQLDHS FQVQSKEFCS YIFSNSKAKT LKEGIVVNGN RLATLVTTYV DAINSGDVPC LENAVTTLAQ RENSIAVQKA ADHYSEQMAQ RMRLPTDTLQ ELLTVHTACE KEAIAVFMEH SFKDENQQFQ KNLVVTIEEK KEDFLRQNEA ASLSHCQAEL DKLSESLRES ISRGVFSVPG GHRLYLEARK KVEQDYERVP RKGVKANHVL QSFLQSQISI EDSIMQSDKA LTDGQKAMEA ERAQKEAAEK EQELLRQKQK ELQQVMEAQE RSYKENVAQL HEKMETERKN ILREQEVKLE HKLKIQKDML NEGFKRKCEA MDLEISQLQK EIQLNKEKNS SLGAKILDGF GDVLISVVPG SGKYFGLGLK ILSSQMNQTQ NSDKVRKL // ID AMPDB_413 PN Guanylate-binding protein 2 PF Guanylate-binding protein 2 GN Gbp2 SO Mus musculus (Mouse) PL 589 PE Evidence at protein level XX AC 'A': 38, 'R': 19, 'N': 23, 'D': 25, 'C': 10, 'Q': 37, 'E': 62, 'G': 29, 'H': 8, 'I': 30, AC 'L': 66, 'K': 57, 'M': 15, 'F': 26, 'P': 17, 'S': 41, 'T': 34, 'W': 4, 'Y': 14, 'V': 34 AF 'A': 6.45%, 'R': 3.23%, 'N': 3.9%, 'D': 4.24%, 'C': 1.7%, 'Q': 6.28%, 'E': 10.53%, 'G': 4.92%, 'H': 1.36%, 'I': 5.09%, AF 'L': 11.21%, 'K': 9.68%, 'M': 2.55%, 'F': 4.41%, 'P': 2.89%, 'S': 6.96%, 'T': 5.77%, 'W': 0.68%, 'Y': 2.38%, 'V': 5.77% MA MO L LO W BA 259 LA 330 AA 84 BC 87 MC 0 MF 0 XX MM 66739.489 AI 86.757 II 41.052 HP -0.411 HM 0.732 IP 5.415 C7 -10.802 SF 0.295, 0.187, 0.307 [Helix, Turn, Sheet] AR 0.075 ME 42860, 43485 XX TO Toxoplasma gondii AM Antimicrobial AM Anti-protozoal EA Hydrolase IE Not found OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 9862701 XR PubMed: 9858320 XR PubMed: 10386861 XR PubMed: 15489334 XR PubMed: 18025219 XR PubMed: 21183079 XR PubMed: 31964735 XR UniProt: Q9Z0E6 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: Q9Z0E6 XR GemBank;EMBL: AJ007970 XR GemBank;EMBL: AF077007 XR GemBank;EMBL: AF109168 XR GemBank;EMBL: CT010249 XR GemBank;EMBL: BC011336 XR GemBank;EMBL: BC032882 XR CCDS: CCDS17880.1 XR RefSeq: NP_034390.1 XR STRING: 10090.ENSMUSP00000132435 XR IntAct: Q9Z0E6 XR MINT: XR DIP: XR BioGRID: 199847 XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR030386 XR InterPro: IPR037684 XR InterPro: IPR003191 XR InterPro: IPR036543 XR InterPro: IPR015894 XR InterPro: IPR027417 XR PANTHER: XR PROSITE: PS51715 XR Ensembl: ENSGT00940000162297 XR KEGG: mmu:14469 XR GeneTree: ENSGT00940000162297 XR BRENDA: XR BioCyc: XR RNAct: Q9Z0E6 SQ SEQUENCE 66739.489 DA MW 589AA MASEIHMSEP MCLIENTEAQ LVINQEALRI LSAITQPVVV VAIVGLYRTG KSYLMNKLAG KRTGFSLGST VQSHTKGIWM WCVPHPKKAG QTLVLLDTEG LEDVEKGDNQ NDCWIFALAV LLSSTFIYNS IGTINQQAMD QLHYVTELTD LIKSKSSPDQ SGVDDSANFV GFFPTFVWTL RDFSLELEVN GKPVTSDEYL EHSLTLKKGA DKKTKSFNEP RLCIRKFFPK RKCFIFDRPA QRKQLSKLET LREEELCGEF VEQVAEFTSY ILSYSSVKTL CGGIIVNGPR LKSLVQTYVG AISNGSLPCM ESAVLTLAQI ENSAAVQKAI THYEEQMNQK IQMPTETLQE LLDLHRPIES EAIEVFLKNS FKDVDQKFQT ELGNLLVAKR DAFIKKNMDV SSARCSDLLE DIFGPLEEEV KLGTFSKPGG YYLFLQMRQE LEKKYNQAPG KGLQAEAMLK NYFDSKADVV ETLLQTDQSL TEAAKEVEEE RTKAEAAEAA NRELEKKQKE FELMMQQKEK SYQEHVKKLT EKMKDEQKQL LAEQENIIAA KLREQEKFLK EGFENESKKL IREIDTLKQN KSSGKCTIL // ID AMPDB_690 PN Magainins PF Magainins GN magainins SO Xenopus laevis (African clawed frog) PL 303 PE Evidence at protein level XX AC 'A': 39, 'R': 20, 'N': 6, 'D': 26, 'C': 2, 'Q': 1, 'E': 37, 'G': 31, 'H': 6, 'I': 15, AC 'L': 13, 'K': 31, 'M': 8, 'F': 26, 'P': 7, 'S': 14, 'T': 0, 'W': 1, 'Y': 0, 'V': 20 AF 'A': 12.87%, 'R': 6.6%, 'N': 1.98%, 'D': 8.58%, 'C': 0.66%, 'Q': 0.33%, 'E': 12.21%, 'G': 10.23%, 'H': 1.98%, 'I': 4.95%, AF 'L': 4.29%, 'K': 10.23%, 'M': 2.64%, 'F': 8.58%, 'P': 2.31%, 'S': 4.62%, 'T': 0%, 'W': 0.33%, 'Y': 0%, 'V': 6.6% MA T, Y MO A LO Q, W BA 160 LA 143 AA 57 BC 63 MC 0 MF 0 XX MM 33379.672 AI 68.053 II 18.275 HP -0.484 HM 0.807 IP 4.993 C7 -11.512 SF 0.248, 0.191, 0.32 [Helix, Turn, Sheet] AR 0.089 ME 5500, 5625 XX TO No Target Organism Found AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Antiviral protein AM Fungicide AM Anti-HSV AM Anti-protozoal EA Not found IE Not found OE Cytolysis OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 2833514 XR PubMed: 3299384 XR PubMed: 1717472 XR PubMed: 15193922 XR PubMed: 8298457 XR UniProt: P11006 XR AlphaFoldDB: P11006 XR Genbank;EMBL: J03193 XR CCDS: XR RefSeq: NP_001081306.1 XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: xla:397766 XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 33379.672 DA MW 303AA MFKGLFICSL IAVICANALP QPEASADEDM DEREVRGIGK FLHSAGKFGK AFVGEIMKSK RDAEAVGPEA FADEDLDERE VRGIGKFLHS AKKFGKAFVG EIMNSKRDAE AVGPEAFADE DLDEREVRGI GKFLHSAKKF GKAFVGEIMN SKRDAEAVGP EAFADEDLDE REVRGIGKFL HSAKKFGKAF VGEIMNSKRD AEAVGPEAFA DEDFDEREVR GIGKFLHSAK KFGKAFVGEI MNSKRDAEAV GPEAFADEDL DEREVRGIGK FLHSAKKFGK AFVGEIMNSK RDAEAVDDRR WVE // ID AMPDB_716 PN Dermaseptin-S1 PF Dermaseptin-S1 GN Not found SO Phyllomedusa sauvagei (Sauvage`s leaf frog) PL 79 PE Evidence at protein level XX AC 'A': 8, 'R': 2, 'N': 1, 'D': 5, 'C': 1, 'Q': 4, 'E': 10, 'G': 5, 'H': 1, 'I': 3, AC 'L': 12, 'K': 9, 'M': 4, 'F': 2, 'P': 0, 'S': 5, 'T': 4, 'W': 1, 'Y': 0, 'V': 2 AF 'A': 10.13%, 'R': 2.53%, 'N': 1.27%, 'D': 6.33%, 'C': 1.27%, 'Q': 5.06%, 'E': 12.66%, 'G': 6.33%, 'H': 1.27%, 'I': 3.8%, AF 'L': 15.19%, 'K': 11.39%, 'M': 5.06%, 'F': 2.53%, 'P': 0%, 'S': 6.33%, 'T': 5.06%, 'W': 1.27%, 'Y': 0%, 'V': 2.53% MA P, Y MO L LO C, H, N, W BA 37 LA 42 AA 12 BC 15 MC 0 MF 0 XX MM 8812.156 AI 91.519 II 49.237 HP -0.372 HM 0.509 IP 4.654 C7 -3.956 SF 0.253, 0.139, 0.43 [Helix, Turn, Sheet] AR 0.038 ME 5500, 5500 XX TO Gram Negative Bacteria and Gram Positive Bacteria AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Antiviral protein AM Fungicide AM Anti-protozoal AM Anti-gram-negative AM Anti-gram-Positive EA Not found IE Not found OE Cytotoxin OE Hemolytic OE Spermicidal OE Non-ribosomal XX XR PubMed: 14599725 XR PubMed: 1909573 XR PubMed: 8306981 XR PubMed: 8294443 XR PubMed: 9647785 XR PubMed: 15193922 XR PubMed: 16307969 XR PubMed: 16140737 XR PubMed: 21262294 XR PubMed: 18644413 XR UniProt: P24302 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P24302 XR Genbank;EMBL: AJ564794 XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR022731 XR InterPro: IPR004275 XR InterPro: IPR016322 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 8812.156 DA MW 79AA MDILKKSLFL VLFLGLVSLS ICEEEKRENE DEEKQEDDEQ SEMKRALWKT MLKKLGTMAL HAGKAALGAA ADTISQGTQ // ID AMPDB_810 PN Gaegurin-4 PF Gaegurin-4 GN GGN4 SO Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa) PL 80 PE Evidence at protein level XX AC 'A': 5, 'R': 2, 'N': 0, 'D': 5, 'C': 3, 'Q': 2, 'E': 8, 'G': 8, 'H': 0, 'I': 2, AC 'L': 11, 'K': 9, 'M': 3, 'F': 5, 'P': 0, 'S': 6, 'T': 6, 'W': 0, 'Y': 0, 'V': 5 AF 'A': 6.25%, 'R': 2.5%, 'N': 0%, 'D': 6.25%, 'C': 3.75%, 'Q': 2.5%, 'E': 10%, 'G': 10%, 'H': 0%, 'I': 2.5%, AF 'L': 13.75%, 'K': 11.25%, 'M': 3.75%, 'F': 6.25%, 'P': 0%, 'S': 7.5%, 'T': 7.5%, 'W': 0%, 'Y': 0%, 'V': 6.25% MA H, N, P, W, Y MO L LO I, Q, R BA 39 LA 41 AA 11 BC 13 MC 0 MF 0 XX MM 8695.107 AI 87.75 II 35.025 HP -0.01 HM 0.723 IP 4.787 C7 -2.174 SF 0.288, 0.175, 0.338 [Helix, Turn, Sheet] AR 0.063 ME 0, 125 XX TO Gram Negative Bacteria and Gram Positive Bacteria AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Anti-protozoal AM Anti-gram-negative AM Anti-gram-Positive EA Not found IE Not found OE Hemolytic OE Non-ribosomal XX XR PubMed: 11004488 XR PubMed: 7999137 XR PubMed: 17141187 XR UniProt: P80398 XR AlphaFoldDB: P80398 XR Genbank;EMBL: U22392 XR Genbank;EMBL: AF213015 XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR012521 XR InterPro: IPR018247 XR InterPro: IPR004275 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 8695.107 DA MW 80AA MFTMKKSLLF LFFLGTISLS LCEEERSADE DDGGEMTEEE VKRGILDTLK QFAKGVGKDL VKGAAQGVLS TVSCKLAKTC // ID AMPDB_856 PN Dermaseptin-O1 PF Dermaseptin-O1 GN Not found SO Pithecopus oreades (Orange-legged leaf frog) (Phyllomedusa oreades) PL 29 PE Evidence at protein level XX AC 'A': 10, 'R': 0, 'N': 0, 'D': 0, 'C': 0, 'Q': 2, 'E': 1, 'G': 4, 'H': 0, 'I': 2, AC 'L': 3, 'K': 4, 'M': 0, 'F': 0, 'P': 0, 'S': 1, 'T': 1, 'W': 1, 'Y': 0, 'V': 0 AF 'A': 34.48%, 'R': 0%, 'N': 0%, 'D': 0%, 'C': 0%, 'Q': 6.9%, 'E': 3.45%, 'G': 13.79%, 'H': 0%, 'I': 6.9%, AF 'L': 10.34%, 'K': 13.79%, 'M': 0%, 'F': 0%, 'P': 0%, 'S': 3.45%, 'T': 3.45%, 'W': 3.45%, 'Y': 0%, 'V': 0% MA C, D, F, H, M, N, P, R, V, Y MO A LO E, S, T, W BA 20 LA 9 AA 4 BC 1 MC 0 MF 0 XX MM 2795.278 AI 101.724 II 14.276 HP 0.286 HM 0.452 IP 10.803 C7 2.999 SF 0.207, 0.172, 0.483 [Helix, Turn, Sheet] AR 0.034 ME 5500, 5500 XX TO No Target Organism Found AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Anti-candida AM Anti-protozoal EA Not found IE Not found OE Hemolytic OE Non-ribosomal XX XR PubMed: 12379643 XR PubMed: 17409003 XR PubMed: 17442605 XR PubMed: 18644413 XR UniProt: P83637 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P83637 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR022731 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 2795.278 DA MW 29AA GLWSTIKQKG KEAAIAAAKA AGQAALGAL // ID AMPDB_872 PN Dermaseptin-H3 PF Dermaseptin-H3 GN Not found SO Pithecopus hypochondrialis (Orange-legged leaf frog) (Phyllomedusa hypochondrialis) PL 70 PE Evidence at protein level XX AC 'A': 8, 'R': 2, 'N': 2, 'D': 3, 'C': 1, 'Q': 2, 'E': 11, 'G': 5, 'H': 0, 'I': 3, AC 'L': 10, 'K': 7, 'M': 3, 'F': 3, 'P': 0, 'S': 5, 'T': 1, 'W': 1, 'Y': 0, 'V': 3 AF 'A': 11.43%, 'R': 2.86%, 'N': 2.86%, 'D': 4.29%, 'C': 1.43%, 'Q': 2.86%, 'E': 15.71%, 'G': 7.14%, 'H': 0%, 'I': 4.29%, AF 'L': 14.29%, 'K': 10%, 'M': 4.29%, 'F': 4.29%, 'P': 0%, 'S': 7.14%, 'T': 1.43%, 'W': 1.43%, 'Y': 0%, 'V': 4.29% MA H, P, Y MO E LO C, T, W BA 36 LA 34 AA 9 BC 14 MC 0 MF 0 XX MM 7760.93 AI 96.286 II 54.49 HP -0.169 HM 0.642 IP 4.336 C7 -5.045 SF 0.286, 0.171, 0.457 [Helix, Turn, Sheet] AR 0.057 ME 5500, 5500 XX TO E.coli (Gram-negative) TO P.aeruginosa (Gram-negative) TO S.aureus (Gram-positive) AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Anti-protozoal AM Anti-gram-negative AM Anti-gram-Positive EA Not found IE Not found OE Hemolytic OE Non-ribosomal XX XR PubMed: 16844081 XR PubMed: 16963159 XR PubMed: 18644413 XR UniProt: P84596 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P84596 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR022731 XR InterPro: IPR004275 XR InterPro: IPR016322 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 7760.93 DA MW 70AA MAFLKKSLFL VLFLGMVSLS ICEEEKRENE DEELQEDDEQ SEMKRGLWST IKNVGKEAAI AAGKAALGAL // ID AMPDB_983 PN Guanylate-binding protein 1 PF Guanylate-binding protein 1 GN GBP1 SO Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) PL 590 PE Evidence at transcript level XX AC 'A': 33, 'R': 28, 'N': 19, 'D': 32, 'C': 9, 'Q': 44, 'E': 56, 'G': 25, 'H': 12, 'I': 28, AC 'L': 65, 'K': 56, 'M': 18, 'F': 23, 'P': 19, 'S': 41, 'T': 32, 'W': 4, 'Y': 15, 'V': 31 AF 'A': 5.59%, 'R': 4.75%, 'N': 3.22%, 'D': 5.42%, 'C': 1.53%, 'Q': 7.46%, 'E': 9.49%, 'G': 4.24%, 'H': 2.03%, 'I': 4.75%, AF 'L': 11.02%, 'K': 9.49%, 'M': 3.05%, 'F': 3.9%, 'P': 3.22%, 'S': 6.95%, 'T': 5.42%, 'W': 0.68%, 'Y': 2.54%, 'V': 5.25% MA MO L LO W BA 246 LA 344 AA 96 BC 88 MC 0 MF 0 XX MM 67820.624 AI 82.305 II 43.573 HP -0.587 HM 0.659 IP 6.793 C7 -3.385 SF 0.281, 0.176, 0.292 [Helix, Turn, Sheet] AR 0.071 ME 44350, 44850 XX TO Listeria monocytogenes (Gram-positive) TO Mycobacterium bovis (Gram-positive) TO Toxoplasma gondii AM Antibiotic AM Antimicrobial AM Anti-listeria AM Anti-protozoal AM Anti-gram-Positive EA Hydrolase IE Not found OE Cell membrane OE Non-hemolytic OE Non-ribosomal XX XR PubMed: XR UniProt: Q5D1D6 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: Q5D1D6 XR Genbank;EMBL: AY920435 XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR030386 XR InterPro: IPR037684 XR InterPro: IPR003191 XR InterPro: IPR036543 XR InterPro: IPR015894 XR InterPro: IPR027417 XR PANTHER: XR PROSITE: PS51715 XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 67820.624 DA MW 590AA MASEIHMTGP MCLIENTNGR LMVNPEALKI LSAITQPVVV VAIVGLYRTG KSYLMNKLAG KKKGFSLGST VQSHTKGIWM WCVPHPKKPG HVLVLLDTEG LGDVEKGDNQ NDSWIFALAI LLSSTFVYNS MGTINQQAMD QLHYVTELTH RIRSKSSPDE NENEDSADFV SFFPDFVWTL RDFSLDLEAD GQPITADEYL TYSLKLKKGT SEKDKTFNLP RLCIRKFFPK KKCFVFDRPV HRKKLAQLEK LHDEELDPEF VQQVADFCSY IFSNSKTKTL SGGIKVNGPR LESLVLTYVN AISSGDLPCM ENAVLALAQI ENSAAVQKAV AHYEQQMGQK VQLPTETLQE LLDLHRDSER EAIEVFIRSS FKDVDHLFQK ELAAQLEKKR DDFCKQNQEA SSDRCSALLQ DIFSPLEEEV KMGIYSKPGG YRLFIQKLQD LKKKYYEEPR KGIQAEEILQ TYLKSKESMT DAILQTDQTL TEKEKEIEVE RVKAESAQAS TKMLQEIQRK NEQMMEQKER SYQEHLKQLT EKMERDRAQL LKEQERTLAL KLQEQERLLK EGFQTESRKM QNEIQDLQKK MRQRRTCTIS // ID AMPDB_1011 PN Guanylate-binding protein 6 PF Guanylate-binding protein 6 GN GBP6 SO Homo sapiens (Human) PL 633 PE Evidence at transcript level XX AC 'A': 42, 'R': 26, 'N': 31, 'D': 29, 'C': 9, 'Q': 44, 'E': 60, 'G': 27, 'H': 16, 'I': 30, AC 'L': 64, 'K': 53, 'M': 19, 'F': 28, 'P': 24, 'S': 36, 'T': 36, 'W': 7, 'Y': 13, 'V': 39 AF 'A': 6.64%, 'R': 4.11%, 'N': 4.9%, 'D': 4.58%, 'C': 1.42%, 'Q': 6.95%, 'E': 9.48%, 'G': 4.27%, 'H': 2.53%, 'I': 4.74%, AF 'L': 10.11%, 'K': 8.37%, 'M': 3%, 'F': 4.42%, 'P': 3.79%, 'S': 5.69%, 'T': 5.69%, 'W': 1.11%, 'Y': 2.05%, 'V': 6.16% MA MO L LO W BA 280 LA 353 AA 95 BC 89 MC 0 MF 0 XX MM 72426.742 AI 82.417 II 39.034 HP -0.507 HM 0.735 IP 6.324 C7 -9.013 SF 0.286, 0.186, 0.292 [Helix, Turn, Sheet] AR 0.076 ME 57870, 58370 XX TO Listeria monocytogenes (Gram-positive) TO Mycobacterium bovis (Gram-positive) TO Toxoplasma gondii AM Antimicrobial AM Anti-listeria AM Anti-protozoal AM Anti-gram-Positive EA Hydrolase IE Not found OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 14702039 XR PubMed: 17974005 XR PubMed: 16710414 XR PubMed: 15489334 XR UniProt: Q6ZN66 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: Q6ZN66 XR GemBank;EMBL: AK131329 XR GemBank;EMBL: AK131356 XR GemBank;EMBL: BX537949 XR GemBank;EMBL: AL691464 XR GemBank;EMBL: BC131713 XR CCDS: CCDS723.1[Q6ZN66-1] XR RefSeq: NP_940862.2[Q6ZN66-1] XR RefSeq: XP_011539137.1[Q6ZN66-1] XR STRING: 9606.ENSP00000359485 XR IntAct: Q6ZN66 XR MINT: XR DIP: XR BioGRID: 127864 XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR030386 XR InterPro: IPR037684 XR InterPro: IPR003191 XR InterPro: IPR036543 XR InterPro: IPR015894 XR InterPro: IPR027417 XR PANTHER: XR PROSITE: PS51715 XR Ensembl: ENSGT00940000154265 XR KEGG: hsa:163351 XR GeneTree: ENSGT00940000154265 XR BRENDA: XR BioCyc: XR RNAct: Q6ZN66 SQ SEQUENCE 72426.742 DA MW 633AA MESGPKMLAP VCLVENNNEQ LLVNQQAIQI LEKISQPVVV VAIVGLYRTG KSYLMNHLAG QNHGFPLGST VQSETKGIWM WCVPHPSKPN HTLVLLDTEG LGDVEKGDPK NDSWIFALAV LLCSTFVYNS MSTINHQALE QLHYVTELTE LIKAKSSPRP DGVEDSTEFV SFFPDFLWTV RDFTLELKLN GHPITEDEYL ENALKLIQGN NPRVQTSNFP RECIRRFFPK RKCFVFDRPT NDKDLLANIE KVSEKQLDPK FQEQTNIFCS YIFTHARTKT LREGITVTGN RLGTLAVTYV EAINSGAVPC LENAVITLAQ RENSAAVQRA ADYYSQQMAQ RVKLPTDTLQ ELLDMHAACE REAIAIFMEH SFKDENQEFQ KKFMETTMNK KGDFLLQNEE SSVQYCQAKL NELSKGLMES ISAGSFSVPG GHKLYMETKE RIEQDYWQVP RKGVKAKEVF QRFLESQMVI EESILQSDKA LTDREKAVAV DRAKKEAAEK EQELLKQKLQ EQQQQMEAQD KSRKENIAQL KEKLQMEREH LLREQIMMLE HTQKVQNDWL HEGFKKKYEE MNAEISQFKR MIDTTKNDDT PWIARTLDNL ADELTAILSA PAKLIGHGVK GVSSLFKKHK LPF // ID AMPDB_1034 PN Trialysin PF Trialysin GN Not found SO Triatoma infestans (Assassin bug) PL 260 PE Evidence at protein level XX AC 'A': 19, 'R': 6, 'N': 10, 'D': 16, 'C': 8, 'Q': 5, 'E': 20, 'G': 23, 'H': 2, 'I': 15, AC 'L': 23, 'K': 34, 'M': 6, 'F': 15, 'P': 7, 'S': 12, 'T': 10, 'W': 1, 'Y': 5, 'V': 23 AF 'A': 7.31%, 'R': 2.31%, 'N': 3.85%, 'D': 6.15%, 'C': 3.08%, 'Q': 1.92%, 'E': 7.69%, 'G': 8.85%, 'H': 0.77%, 'I': 5.77%, AF 'L': 8.85%, 'K': 13.08%, 'M': 2.31%, 'F': 5.77%, 'P': 2.69%, 'S': 4.62%, 'T': 3.85%, 'W': 0.38%, 'Y': 1.92%, 'V': 8.85% MA MO K LO W BA 132 LA 128 AA 42 BC 36 MC 0 MF 0 XX MM 28593.373 AI 89.962 II 20.775 HP -0.115 HM 0.774 IP 8.376 C7 3.712 SF 0.315, 0.2, 0.262 [Helix, Turn, Sheet] AR 0.081 ME 12950, 13450 XX TO E.coli (Gram-negative) TO T.cruzi AM Antibiotic AM Antimicrobial AM Anti-parasitic AM Anti-protozoal AM Anti-gram-negative EA Not found IE Not found OE Cytolysis OE Hemolytic OE Non-ribosomal XX XR PubMed: 11751887 XR UniProt: Q8T0Z3 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: Q8T0Z3 XR Genbank;EMBL: AF427486 XR Genbank;EMBL: AF427487 XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 28593.373 DA MW 260AA MSKFWLLLLL VAAFQFAHSY PAAEYELDET TNDEVRQFIG DGYFEDEGDD GDEERFKIKP GKVLDKFGKI VGKVLKQLKK VSAVAKVAMK KGAALLKKMG VKISPLKCEE KTCKSCVIFK IPTENSFCLT IRFMKTNIAT YLVVAGEINR KSKFEEKLKL GNMPRCVNVE GFIGKVCMKG IEGHAKSSSG QANVNFCLGL VAEKFGVGAK LCGIYANKKV RVKISPQLFP GATSLDGDIV KLDDNGEDAT TLDVDEVEID // ID AMPDB_3911 PN Dermaseptin-S3 PF Dermaseptin-S3 GN Not found SO Phyllomedusa sauvagei (Sauvage`s leaf frog) PL 30 PE Evidence at protein level XX AC 'A': 6, 'R': 0, 'N': 1, 'D': 0, 'C': 0, 'Q': 0, 'E': 1, 'G': 5, 'H': 0, 'I': 1, AC 'L': 5, 'K': 6, 'M': 1, 'F': 0, 'P': 0, 'S': 1, 'T': 0, 'W': 1, 'Y': 0, 'V': 2 AF 'A': 20%, 'R': 0%, 'N': 3.33%, 'D': 0%, 'C': 0%, 'Q': 0%, 'E': 3.33%, 'G': 16.67%, 'H': 0%, 'I': 3.33%, AF 'L': 16.67%, 'K': 20%, 'M': 3.33%, 'F': 0%, 'P': 0%, 'S': 3.33%, 'T': 0%, 'W': 3.33%, 'Y': 0%, 'V': 6.67% MA C, D, F, H, P, Q, R, T, Y MO A; K LO E, I, M, N, S, W BA 21 LA 9 AA 6 BC 1 MC 0 MF 0 XX MM 3023.717 AI 117.333 II -5.28 HP 0.35 HM 0.704 IP 11.102 C7 4.998 SF 0.3, 0.233, 0.433 [Helix, Turn, Sheet] AR 0.033 ME 5500, 5500 XX TO No Target Organism Found AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Fungicide AM Anti-parasitic AM Anti-protozoal EA Not found IE Not found OE Hemolytic OE Non-ribosomal XX XR PubMed: 8306981 XR PubMed: 9395500 XR PubMed: 18644413 XR UniProt: P80279 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P80279 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR022731 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 3023.717 DA MW 30AA ALWKNMLKGI GKLAGKAALG AVKKLVGAES // ID AMPDB_3912 PN Dermaseptin-S4 PF Dermaseptin-S4 GN Not found SO Phyllomedusa sauvagei (Sauvage`s leaf frog) PL 27 PE Evidence at protein level XX AC 'A': 8, 'R': 0, 'N': 2, 'D': 0, 'C': 0, 'Q': 0, 'E': 0, 'G': 1, 'H': 0, 'I': 0, AC 'L': 6, 'K': 4, 'M': 1, 'F': 0, 'P': 0, 'S': 0, 'T': 1, 'W': 1, 'Y': 0, 'V': 3 AF 'A': 29.63%, 'R': 0%, 'N': 7.41%, 'D': 0%, 'C': 0%, 'Q': 0%, 'E': 0%, 'G': 3.7%, 'H': 0%, 'I': 0%, AF 'L': 22.22%, 'K': 14.81%, 'M': 3.7%, 'F': 0%, 'P': 0%, 'S': 0%, 'T': 3.7%, 'W': 3.7%, 'Y': 0%, 'V': 11.11% MA C, D, E, F, H, I, P, Q, R, S, Y MO A LO G, M, T, W BA 20 LA 7 AA 4 BC 0 MC 0 MF 0 XX MM 2779.467 AI 148.519 II 10.381 HP 1.004 HM 0.708 IP 11.278 C7 3.997 SF 0.37, 0.111, 0.556 [Helix, Turn, Sheet] AR 0.037 ME 5500, 5500 XX TO No Target Organism Found AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Fungicide AM Anti-HSV AM Anti-parasitic AM Anti-protozoal EA Not found IE Not found OE Cytolysis OE Hemolytic OE Spermicidal OE Non-ribosomal XX XR PubMed: 8306981 XR PubMed: 9395500 XR PubMed: 11587797 XR PubMed: 11850249 XR PubMed: 12119035 XR PubMed: 11937508 XR PubMed: 11782932 XR PubMed: 16307969 XR PubMed: 15780876 XR PubMed: 16870756 XR PubMed: 18644413 XR PubMed: 16407175 XR UniProt: P80280 XR AlphaFoldDB: P80280 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 2779.467 DA MW 27AA ALWMTLLKKV LKAAAKALNA VLVGANA // ID AMPDB_3913 PN Dermaseptin-B1 PF Dermaseptin-B1 GN Not found SO Phyllomedusa bicolor (Two-colored leaf frog) (Rana bicolor) PL 78 PE Evidence at protein level XX AC 'A': 7, 'R': 2, 'N': 1, 'D': 6, 'C': 1, 'Q': 4, 'E': 10, 'G': 5, 'H': 1, 'I': 4, AC 'L': 10, 'K': 9, 'M': 3, 'F': 2, 'P': 0, 'S': 5, 'T': 2, 'W': 1, 'Y': 0, 'V': 5 AF 'A': 8.97%, 'R': 2.56%, 'N': 1.28%, 'D': 7.69%, 'C': 1.28%, 'Q': 5.13%, 'E': 12.82%, 'G': 6.41%, 'H': 1.28%, 'I': 5.13%, AF 'L': 12.82%, 'K': 11.54%, 'M': 3.85%, 'F': 2.56%, 'P': 0%, 'S': 6.41%, 'T': 2.56%, 'W': 1.28%, 'Y': 0%, 'V': 6.41% MA P, Y MO E; L LO C, H, N, W BA 37 LA 41 AA 12 BC 16 MC 0 MF 0 XX MM 8707.001 AI 97.564 II 46.21 HP -0.329 HM 0.647 IP 4.522 C7 -4.955 SF 0.282, 0.141, 0.385 [Helix, Turn, Sheet] AR 0.038 ME 5500, 5500 XX TO No Target Organism Found AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Fungicide AM Anti-protozoal EA Not found IE Not found OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 8074751 XR PubMed: 8306981 XR PubMed: 18644413 XR UniProt: P80282 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P80282 XR Genbank;EMBL: X72387 XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR022731 XR InterPro: IPR004275 XR InterPro: IPR016322 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 8707.001 DA MW 78AA MDILKKSLFL VLFLGLVSLS ICEEEKRENE DEEKQDDEQS EMKRAMWKDV LKKIGTVALH AGKAALGAVA DTISQGEQ // ID AMPDB_3917 PN Gaegurin-1 PF Gaegurin-1 GN GGN1 SO Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa) PL 33 PE Evidence at protein level XX AC 'A': 6, 'R': 0, 'N': 1, 'D': 0, 'C': 3, 'Q': 2, 'E': 0, 'G': 3, 'H': 0, 'I': 1, AC 'L': 5, 'K': 6, 'M': 0, 'F': 2, 'P': 0, 'S': 3, 'T': 0, 'W': 0, 'Y': 1, 'V': 0 AF 'A': 18.18%, 'R': 0%, 'N': 3.03%, 'D': 0%, 'C': 9.09%, 'Q': 6.06%, 'E': 0%, 'G': 9.09%, 'H': 0%, 'I': 3.03%, AF 'L': 15.15%, 'K': 18.18%, 'M': 0%, 'F': 6.06%, 'P': 0%, 'S': 9.09%, 'T': 0%, 'W': 0%, 'Y': 3.03%, 'V': 0% MA D, E, H, M, P, R, T, V, W MO A; K LO I, N, Y BA 17 LA 16 AA 6 BC 0 MC 0 MF 0 XX MM 3462.19 AI 89.091 II 42.706 HP 0.261 HM 0.602 IP 10.304 C7 5.809 SF 0.273, 0.212, 0.333 [Helix, Turn, Sheet] AR 0.091 ME 1490, 1615 XX TO Gram Negative Bacteria and Gram Positive Bacteria AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Anti-protozoal AM Anti-gram-negative AM Anti-gram-Positive EA Not found IE Not found OE Hemolytic OE Non-ribosomal XX XR PubMed: 7999137 XR UniProt: P80395 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P80395 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR012521 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 3462.19 DA MW 33AA SLFSLIKAGA KFLGKNLLKQ GACYAACKAS KQC // ID AMPDB_3918 PN Gaegurin-2 PF Gaegurin-2 GN GGN2 SO Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa) PL 33 PE Evidence at protein level XX AC 'A': 7, 'R': 0, 'N': 1, 'D': 1, 'C': 2, 'Q': 0, 'E': 1, 'G': 2, 'H': 0, 'I': 2, AC 'L': 3, 'K': 6, 'M': 1, 'F': 0, 'P': 0, 'S': 3, 'T': 2, 'W': 0, 'Y': 0, 'V': 2 AF 'A': 21.21%, 'R': 0%, 'N': 3.03%, 'D': 3.03%, 'C': 6.06%, 'Q': 0%, 'E': 3.03%, 'G': 6.06%, 'H': 0%, 'I': 6.06%, AF 'L': 9.09%, 'K': 18.18%, 'M': 3.03%, 'F': 0%, 'P': 0%, 'S': 9.09%, 'T': 6.06%, 'W': 0%, 'Y': 0%, 'V': 6.06% MA F, H, P, Q, R, W, Y MO A LO D, E, M, N BA 17 LA 16 AA 6 BC 2 MC 0 MF 0 XX MM 3322 AI 97.879 II 19.155 HP 0.297 HM 0.665 IP 10.138 C7 3.874 SF 0.212, 0.182, 0.364 [Helix, Turn, Sheet] AR 0 ME 0, 125 XX TO Gram Negative Bacteria and Gram Positive Bacteria AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Anti-protozoal AM Anti-gram-negative AM Anti-gram-Positive EA Not found IE Not found OE Hemolytic OE Non-ribosomal XX XR PubMed: 7999137 XR UniProt: P80396 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P80396 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR012521 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 3322 DA MW 33AA GIMSIVKDVA KNAAKEAAKG ALSTLSCKLA KTC // ID AMPDB_3919 PN Gaegurin-3 PF Gaegurin-3 GN GGN3 SO Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa) PL 33 PE Evidence at protein level XX AC 'A': 7, 'R': 0, 'N': 0, 'D': 1, 'C': 2, 'Q': 0, 'E': 1, 'G': 2, 'H': 0, 'I': 2, AC 'L': 3, 'K': 6, 'M': 1, 'F': 0, 'P': 0, 'S': 3, 'T': 3, 'W': 0, 'Y': 0, 'V': 2 AF 'A': 21.21%, 'R': 0%, 'N': 0%, 'D': 3.03%, 'C': 6.06%, 'Q': 0%, 'E': 3.03%, 'G': 6.06%, 'H': 0%, 'I': 6.06%, AF 'L': 9.09%, 'K': 18.18%, 'M': 3.03%, 'F': 0%, 'P': 0%, 'S': 9.09%, 'T': 9.09%, 'W': 0%, 'Y': 0%, 'V': 6.06% MA F, H, N, P, Q, R, W, Y MO A LO D, E, M BA 17 LA 16 AA 6 BC 2 MC 0 MF 0 XX MM 3309.002 AI 97.879 II 19.155 HP 0.382 HM 0.661 IP 10.138 C7 3.874 SF 0.212, 0.152, 0.364 [Helix, Turn, Sheet] AR 0 ME 0, 125 XX TO Gram Negative Bacteria and Gram Positive Bacteria AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Anti-protozoal AM Anti-gram-negative AM Anti-gram-Positive EA Not found IE Not found OE Hemolytic OE Non-ribosomal XX XR PubMed: 7999137 XR UniProt: P80397 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P80397 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR012521 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 3309.002 DA MW 33AA GIMSIVKDVA KTAAKEAAKG ALSTLSCKLA KTC // ID AMPDB_3920 PN Gaegurin-5 PF Gaegurin-5 GN GGN5 SO Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa) PL 65 PE Evidence at protein level XX AC 'A': 4, 'R': 3, 'N': 1, 'D': 2, 'C': 3, 'Q': 0, 'E': 8, 'G': 2, 'H': 0, 'I': 2, AC 'L': 11, 'K': 8, 'M': 1, 'F': 6, 'P': 1, 'S': 5, 'T': 3, 'W': 0, 'Y': 0, 'V': 5 AF 'A': 6.15%, 'R': 4.62%, 'N': 1.54%, 'D': 3.08%, 'C': 4.62%, 'Q': 0%, 'E': 12.31%, 'G': 3.08%, 'H': 0%, 'I': 3.08%, AF 'L': 16.92%, 'K': 12.31%, 'M': 1.54%, 'F': 9.23%, 'P': 1.54%, 'S': 7.69%, 'T': 4.62%, 'W': 0%, 'Y': 0%, 'V': 7.69% MA H, Q, W, Y MO L LO M, N, P BA 32 LA 33 AA 11 BC 10 MC 0 MF 0 XX MM 7413.821 AI 106.462 II 37.614 HP 0.208 HM 0.632 IP 8.039 C7 0.825 SF 0.369, 0.138, 0.369 [Helix, Turn, Sheet] AR 0.092 ME 0, 125 XX TO Gram Negative Bacteria and Gram Positive Bacteria AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Anti-protozoal AM Anti-gram-negative AM Anti-gram-Positive EA Not found IE Not found OE Hemolytic OE Non-ribosomal XX XR PubMed: 7999137 XR UniProt: P80399 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P80399 XR Genbank;EMBL: U22393 XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR012520 XR InterPro: IPR004275 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 7413.821 DA MW 65AA MFTLKKSLLL LFFLGTISLS LCEEERNADE EEKRDVEVEK RFLGALFKVA SKVLPSVFCA ITKKC // ID AMPDB_3921 PN Gaegurin-6 PF Gaegurin-6 GN GGN6 SO Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa) PL 24 PE Evidence at protein level XX AC 'A': 3, 'R': 0, 'N': 1, 'D': 0, 'C': 2, 'Q': 0, 'E': 0, 'G': 1, 'H': 0, 'I': 3, AC 'L': 5, 'K': 2, 'M': 0, 'F': 2, 'P': 2, 'S': 1, 'T': 1, 'W': 0, 'Y': 1, 'V': 0 AF 'A': 12.5%, 'R': 0%, 'N': 4.17%, 'D': 0%, 'C': 8.33%, 'Q': 0%, 'E': 0%, 'G': 4.17%, 'H': 0%, 'I': 12.5%, AF 'L': 20.83%, 'K': 8.33%, 'M': 0%, 'F': 8.33%, 'P': 8.33%, 'S': 4.17%, 'T': 4.17%, 'W': 0%, 'Y': 4.17%, 'V': 0% MA D, E, H, M, Q, R, V, W MO L LO G, N, S, T, Y BA 16 LA 8 AA 2 BC 0 MC 0 MF 0 XX MM 2610.254 AI 142.5 II 15.833 HP 1.283 HM 0.5 IP 8.792 C7 1.873 SF 0.458, 0.208, 0.333 [Helix, Turn, Sheet] AR 0.125 ME 1490, 1615 XX TO Gram Negative Bacteria and Gram Positive Bacteria AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Anti-protozoal AM Anti-gram-negative AM Anti-gram-Positive EA Not found IE Not found OE Hemolytic OE Non-ribosomal XX XR PubMed: 7999137 XR UniProt: P80400 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P80400 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR012520 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 2610.254 DA MW 24AA FLPLLAGLAA NFLPTIICKI SYKC // ID AMPDB_4080 PN Dermaseptin-DI1 PF Dermaseptin-DI1 GN Not found SO Phyllomedusa distincta (Monkey frog) PL 33 PE Evidence at protein level XX AC 'A': 13, 'R': 0, 'N': 1, 'D': 0, 'C': 0, 'Q': 0, 'E': 2, 'G': 3, 'H': 0, 'I': 1, AC 'L': 2, 'K': 6, 'M': 0, 'F': 0, 'P': 0, 'S': 2, 'T': 0, 'W': 1, 'Y': 0, 'V': 2 AF 'A': 39.39%, 'R': 0%, 'N': 3.03%, 'D': 0%, 'C': 0%, 'Q': 0%, 'E': 6.06%, 'G': 9.09%, 'H': 0%, 'I': 3.03%, AF 'L': 6.06%, 'K': 18.18%, 'M': 0%, 'F': 0%, 'P': 0%, 'S': 6.06%, 'T': 0%, 'W': 3.03%, 'Y': 0%, 'V': 6.06% MA C, D, F, H, M, P, Q, R, T, Y MO A LO I, N, W BA 22 LA 11 AA 6 BC 2 MC 0 MF 0 XX MM 3152.688 AI 92.424 II 12.418 HP 0.191 HM 0.562 IP 10.802 C7 4 SF 0.182, 0.182, 0.515 [Helix, Turn, Sheet] AR 0.03 ME 5500, 5500 XX TO C.albicans TO C.guilliermondii TO C.tropicalis (Gram-negative) TO E.faecalis (Gram-positive) TO P.aeruginosa (Gram-negative) TO S.aureus (Gram-positive) AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Anti-candida AM Anti-protozoal AM Anti-gram-negative AM Anti-gram-Positive EA Not found IE Not found OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 10477123 XR PubMed: 12379643 XR PubMed: 17409003 XR PubMed: 17442605 XR PubMed: 18644413 XR PubMed: 19289046 XR UniProt: P83638 XR AlphaFoldDB: P83638 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR022731 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 3152.688 DA MW 33AA GLWSKIKAAG KEAAKAAAKA AGKAALNAVS EAV // ID AMPDB_4081 PN Dermaseptin-DI2 PF Dermaseptin-DI2 GN Not found SO Phyllomedusa distincta (Monkey frog) PL 28 PE Evidence at protein level XX AC 'A': 6, 'R': 0, 'N': 3, 'D': 1, 'C': 0, 'Q': 1, 'E': 0, 'G': 2, 'H': 0, 'I': 0, AC 'L': 4, 'K': 4, 'M': 1, 'F': 0, 'P': 0, 'S': 0, 'T': 2, 'W': 1, 'Y': 0, 'V': 3 AF 'A': 21.43%, 'R': 0%, 'N': 10.71%, 'D': 3.57%, 'C': 0%, 'Q': 3.57%, 'E': 0%, 'G': 7.14%, 'H': 0%, 'I': 0%, AF 'L': 14.29%, 'K': 14.29%, 'M': 3.57%, 'F': 0%, 'P': 0%, 'S': 0%, 'T': 7.14%, 'W': 3.57%, 'Y': 0%, 'V': 10.71% MA C, E, F, H, I, P, R, S, Y MO A LO D, M, Q, W BA 17 LA 11 AA 4 BC 1 MC 0 MF 0 XX MM 2926.47 AI 108.214 II 0.246 HP 0.154 HM 0.65 IP 10.803 C7 2.997 SF 0.286, 0.179, 0.393 [Helix, Turn, Sheet] AR 0.036 ME 5500, 5500 XX TO C.albicans TO C.guilliermondii TO C.tropicalis (Gram-negative) TO E.faecalis (Gram-positive) TO P.aeruginosa (Gram-negative) TO S.aureus (Gram-positive) AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Anti-candida AM Anti-protozoal AM Anti-gram-negative AM Anti-gram-Positive EA Not found IE Not found OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 10477123 XR PubMed: 12379643 XR PubMed: 17409003 XR PubMed: 17442605 XR PubMed: 18644413 XR UniProt: P83639 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P83639 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR022731 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 2926.47 DA MW 28AA ALWKTLLKNV GKAAGKAALN AVTDMVNQ // ID AMPDB_4128 PN Phylloseptin-O1 PF Phylloseptin-O1 GN psn4 psn-4 SO Pithecopus oreades (Orange-legged leaf frog) (Phyllomedusa oreades) PL 20 PE Evidence at protein level XX AC 'A': 2, 'R': 0, 'N': 1, 'D': 0, 'C': 0, 'Q': 0, 'E': 0, 'G': 1, 'H': 3, 'I': 2, AC 'L': 3, 'K': 0, 'M': 0, 'F': 1, 'P': 1, 'S': 3, 'T': 1, 'W': 0, 'Y': 0, 'V': 2 AF 'A': 10%, 'R': 0%, 'N': 5%, 'D': 0%, 'C': 0%, 'Q': 0%, 'E': 0%, 'G': 5%, 'H': 15%, 'I': 10%, AF 'L': 15%, 'K': 0%, 'M': 0%, 'F': 5%, 'P': 5%, 'S': 15%, 'T': 5%, 'W': 0%, 'Y': 0%, 'V': 10% MA C, D, E, K, M, Q, R, W, Y MO H; L; S LO F, G, N, P, T BA 12 LA 8 AA 3 BC 0 MC 0 MF 0 XX MM 2113.447 AI 136.5 II 8.06 HP 0.85 HM 0.457 IP 7.811 C7 0.271 SF 0.4, 0.3, 0.25 [Helix, Turn, Sheet] AR 0.05 ME 0, 0 XX TO No Target Organism Found AM Amphibian defense peptide AM Antimicrobial AM Anti-protozoal EA Not found IE Not found OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 15752569 XR PubMed: 18644413 XR UniProt: P84569 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P84569 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 2113.447 DA MW 20AA FLSLIPHAIN AVSTLVHHSG // ID AMPDB_4129 PN Phylloseptin-O2 PF Phylloseptin-O2 GN psn5 psn-5 SO Pithecopus oreades (Orange-legged leaf frog) (Phyllomedusa oreades) PL 19 PE Evidence at protein level XX AC 'A': 4, 'R': 0, 'N': 1, 'D': 0, 'C': 0, 'Q': 0, 'E': 0, 'G': 0, 'H': 2, 'I': 3, AC 'L': 2, 'K': 1, 'M': 0, 'F': 1, 'P': 1, 'S': 3, 'T': 0, 'W': 0, 'Y': 0, 'V': 1 AF 'A': 21.05%, 'R': 0%, 'N': 5.26%, 'D': 0%, 'C': 0%, 'Q': 0%, 'E': 0%, 'G': 0%, 'H': 10.53%, 'I': 15.79%, AF 'L': 10.53%, 'K': 5.26%, 'M': 0%, 'F': 5.26%, 'P': 5.26%, 'S': 15.79%, 'T': 0%, 'W': 0%, 'Y': 0%, 'V': 5.26% MA C, D, E, G, M, Q, R, T, W, Y MO A LO F, K, N, P, V BA 12 LA 7 AA 3 BC 0 MC 0 MF 0 XX MM 1989.348 AI 138.947 II 7.958 HP 0.921 HM 0.484 IP 9.704 C7 1.18 SF 0.368, 0.263, 0.316 [Helix, Turn, Sheet] AR 0.053 ME 0, 0 XX TO No Target Organism Found AM Amphibian defense peptide AM Antimicrobial AM Anti-protozoal EA Not found IE Not found OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 15752569 XR PubMed: 18644413 XR UniProt: P84570 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P84570 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 1989.348 DA MW 19AA FLSLIPHAIN AVSAIAKHS // ID AMPDB_4133 PN Dermaseptin-H7 PF Dermaseptin-H7 GN Not found SO Pithecopus hypochondrialis (Orange-legged leaf frog) (Phyllomedusa hypochondrialis) PL 29 PE Evidence at protein level XX AC 'A': 10, 'R': 0, 'N': 0, 'D': 0, 'C': 0, 'Q': 2, 'E': 1, 'G': 4, 'H': 0, 'I': 2, AC 'L': 3, 'K': 4, 'M': 0, 'F': 0, 'P': 0, 'S': 1, 'T': 1, 'W': 1, 'Y': 0, 'V': 0 AF 'A': 34.48%, 'R': 0%, 'N': 0%, 'D': 0%, 'C': 0%, 'Q': 6.9%, 'E': 3.45%, 'G': 13.79%, 'H': 0%, 'I': 6.9%, AF 'L': 10.34%, 'K': 13.79%, 'M': 0%, 'F': 0%, 'P': 0%, 'S': 3.45%, 'T': 3.45%, 'W': 3.45%, 'Y': 0%, 'V': 0% MA C, D, F, H, M, N, P, R, V, Y MO A LO E, S, T, W BA 20 LA 9 AA 4 BC 1 MC 0 MF 0 XX MM 2795.278 AI 101.724 II 14.276 HP 0.286 HM 0.452 IP 10.803 C7 2.999 SF 0.207, 0.172, 0.483 [Helix, Turn, Sheet] AR 0.034 ME 5500, 5500 XX TO E.coli (Gram-negative) TO L.amazonensis TO S.aureus (Gram-positive) AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Fungicide AM Anti-protozoal AM Anti-gram-negative AM Anti-gram-Positive EA Not found IE Not found OE Hemolytic OE Non-ribosomal XX XR PubMed: 16844081 XR PubMed: 18644413 XR UniProt: P84600 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P84600 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR022731 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 2795.278 DA MW 29AA GLWSTIKQKG KEAAIAAAKA AGQAALGAL // ID AMPDB_4230 PN Dermaseptin DS VIII-like peptide PF Dermaseptin DS VIII-like peptide GN Not found SO Phyllomedusa burmeisteri (Brazilian common walking leaf frog) PL 33 PE Evidence at protein level XX AC 'A': 9, 'R': 0, 'N': 0, 'D': 1, 'C': 0, 'Q': 1, 'E': 0, 'G': 4, 'H': 1, 'I': 1, AC 'L': 5, 'K': 4, 'M': 1, 'F': 0, 'P': 0, 'S': 1, 'T': 3, 'W': 1, 'Y': 0, 'V': 1 AF 'A': 27.27%, 'R': 0%, 'N': 0%, 'D': 3.03%, 'C': 0%, 'Q': 3.03%, 'E': 0%, 'G': 12.12%, 'H': 3.03%, 'I': 3.03%, AF 'L': 15.15%, 'K': 12.12%, 'M': 3.03%, 'F': 0%, 'P': 0%, 'S': 3.03%, 'T': 9.09%, 'W': 3.03%, 'Y': 0%, 'V': 3.03% MA C, E, F, N, P, R, Y MO A LO D, H, I, M, Q, S, V, W BA 22 LA 11 AA 5 BC 1 MC 0 MF 0 XX MM 3264.877 AI 106.97 II 0.145 HP 0.442 HM 0.528 IP 10.803 C7 3.088 SF 0.242, 0.152, 0.455 [Helix, Turn, Sheet] AR 0.03 ME 5500, 5500 XX TO No Target Organism Found AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Anti-protozoal EA Not found IE Not found OE Non-hemolytic OE Non-ribosomal XX XR PubMed: XR UniProt: P86280 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P86280 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR022731 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 3264.877 DA MW 33AA ALWKTMLKKL GTVALHAGKA ALGAAADTIS QGA // ID AMPDB_4366 PN Serine protease inhibitor Cvsi-1 PF Not found GN Not found SO Crassostrea virginica (Eastern oyster) PL 90 PE Evidence at protein level XX AC 'A': 4, 'R': 2, 'N': 3, 'D': 4, 'C': 14, 'Q': 2, 'E': 2, 'G': 8, 'H': 5, 'I': 2, AC 'L': 9, 'K': 2, 'M': 1, 'F': 6, 'P': 1, 'S': 5, 'T': 8, 'W': 1, 'Y': 1, 'V': 10 AF 'A': 4.44%, 'R': 2.22%, 'N': 3.33%, 'D': 4.44%, 'C': 15.56%, 'Q': 2.22%, 'E': 2.22%, 'G': 8.89%, 'H': 5.56%, 'I': 2.22%, AF 'L': 10%, 'K': 2.22%, 'M': 1.11%, 'F': 6.67%, 'P': 1.11%, 'S': 5.56%, 'T': 8.89%, 'W': 1.11%, 'Y': 1.11%, 'V': 11.11% MA MO C LO M, P, W, Y BA 42 LA 48 AA 9 BC 6 MC 0 MF 0 XX MM 9715.345 AI 84.333 II 39.888 HP 0.647 HM 0.529 IP 6.613 C7 -2.411 SF 0.322, 0.189, 0.178 [Helix, Turn, Sheet] AR 0.089 ME 6990, 7865 XX TO No Target Organism Found AM Antimicrobial AM Anti-parasitic AM Anti-protozoal EA Not found IE Protease inhibitor IE Serine protease inhibitor OE Enzyme inhibitor OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 16872855 XR PubMed: 19720077 XR UniProt: Q30HU9 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: Q30HU9 XR Genbank;EMBL: DQ092546 XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 9715.345 DA MW 90AA MDVVRTLILC VCLFGLTFAV PCIDGVCTSN ELQCASGYVK GCHAGLCTCE HATTQSCTVV NNCLHLGTCS LHGRDGFWHC VDSVCKCFFF // ID AMPDB_4453 PN Guanylate-binding protein 6 PF Guanylate-binding protein 6 GN GBP6 SO Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) PL 633 PE Evidence at transcript level XX AC 'A': 42, 'R': 25, 'N': 30, 'D': 30, 'C': 8, 'Q': 46, 'E': 58, 'G': 27, 'H': 15, 'I': 34, AC 'L': 64, 'K': 54, 'M': 18, 'F': 28, 'P': 24, 'S': 37, 'T': 34, 'W': 7, 'Y': 13, 'V': 39 AF 'A': 6.64%, 'R': 3.95%, 'N': 4.74%, 'D': 4.74%, 'C': 1.26%, 'Q': 7.27%, 'E': 9.16%, 'G': 4.27%, 'H': 2.37%, 'I': 5.37%, AF 'L': 10.11%, 'K': 8.53%, 'M': 2.84%, 'F': 4.42%, 'P': 3.79%, 'S': 5.85%, 'T': 5.37%, 'W': 1.11%, 'Y': 2.05%, 'V': 6.16% MA MO L LO W BA 283 LA 350 AA 94 BC 88 MC 0 MF 0 XX MM 72363.777 AI 84.882 II 38.38 HP -0.478 HM 0.789 IP 6.366 C7 -8.045 SF 0.292, 0.186, 0.288 [Helix, Turn, Sheet] AR 0.076 ME 57870, 58370 XX TO Listeria monocytogenes (Gram-positive) TO Mycobacterium bovis (Gram-positive) TO Toxoplasma gondii AM Antimicrobial AM Anti-listeria AM Anti-protozoal AM Anti-gram-Positive EA Hydrolase IE Not found OE Non-hemolytic OE Non-ribosomal XX XR PubMed: XR UniProt: Q5R9T9 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: Q5R9T9 XR Genbank;EMBL: CR859293 XR CCDS: XR RefSeq: NP_001125866.1 XR STRING: 9601.ENSPPYP00000001356 XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR030386 XR InterPro: IPR037684 XR InterPro: IPR003191 XR InterPro: IPR036543 XR InterPro: IPR015894 XR InterPro: IPR027417 XR PANTHER: XR PROSITE: PS51715 XR Ensembl: XR KEGG: pon:100172797 XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 72363.777 DA MW 633AA MESGPKMLAP ICLVENNNEQ LLVNQQAIQI LEKISQPVVV VAIVGLYRTG KSYLMNHLAG QNHGFPLGST VQSETKGIWM WCVPHPSKPN HTLVLLDTEG LGDVEKGDPK NDSWIFALAV LLCSTFIYNS MSTINHQALE QLHYVTELTE LIKAKSSPRP DGVDDSTEFV SFFPDFIWTV RDFTLELKLN GHPITEDEYL ENALKLIQGN NPRVQTSNLP RECIRRFFPK RKCFIFDRPT NDKDLLANIE KVSEKQLDPK FQEQTNIFSS YIFTHARTKT LREGIIVTGN RLGTLAVTYV EAVNSGAVPC LENAVITLAQ RENSAAVQRA ADYYSQQMAQ RVKFPTDTLQ ELLDMHAACE REAIAIFMEH SFKDENQEFQ KKFMETTMNK KGDFLLQNEE SSVQYCQAKL NELSKGLMES ISAGSFSVPG GHKLYMETKE RIEQDYWQVP RKGVKAKEVF QRFLESQVVI EESILQSDKA LTDREKAVAV DRAKKEAAEK EQELLKQKLQ EQQQQMEAQD KSLKENIAQL KQKLQMEREQ LLREQIMMLE HTQKVQNDWL HEGFKKKYEE MNAEISQFKR MIDITKNDDT PWIARTLDKL ADELTAVLSA PAKLIGHGVK GVSSLFKKHK LPF // ID AMPDB_4531 PN Dermaseptin-S8 PF Dermaseptin-S8 GN Not found SO Phyllomedusa sauvagei (Sauvage`s leaf frog) PL 79 PE Evidence at protein level XX AC 'A': 9, 'R': 2, 'N': 1, 'D': 5, 'C': 1, 'Q': 4, 'E': 10, 'G': 5, 'H': 1, 'I': 3, AC 'L': 12, 'K': 9, 'M': 3, 'F': 2, 'P': 0, 'S': 5, 'T': 3, 'W': 1, 'Y': 0, 'V': 3 AF 'A': 11.39%, 'R': 2.53%, 'N': 1.27%, 'D': 6.33%, 'C': 1.27%, 'Q': 5.06%, 'E': 12.66%, 'G': 6.33%, 'H': 1.27%, 'I': 3.8%, AF 'L': 15.19%, 'K': 11.39%, 'M': 3.8%, 'F': 2.53%, 'P': 0%, 'S': 6.33%, 'T': 3.8%, 'W': 1.27%, 'Y': 0%, 'V': 3.8% MA P, Y MO L LO C, H, N, W BA 38 LA 41 AA 12 BC 15 MC 0 MF 0 XX MM 8750.07 AI 96.456 II 48.629 HP -0.311 HM 0.528 IP 4.654 C7 -3.956 SF 0.266, 0.139, 0.43 [Helix, Turn, Sheet] AR 0.038 ME 5500, 5500 XX TO No Target Organism Found AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Anti-protozoal EA Not found IE Not found OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 14599725 XR PubMed: 18644413 XR UniProt: Q7T3K7 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: Q7T3K7 XR Genbank;EMBL: AJ564793 XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR022731 XR InterPro: IPR004275 XR InterPro: IPR016322 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 8750.07 DA MW 79AA MDILKKSLFL VLFLGLVSLS ICEEEKRENE DEEKQEDDEQ SEMKRALWKT MLKKLGTVAL HAGKAALGAA ADTISQGAQ // ID AMPDB_34922 PN Dermaseptin-S2 PF Dermaseptin-S2 GN Not found SO Phyllomedusa sauvagei (Sauvage`s leaf frog) PL 34 PE Evidence at protein level XX AC 'A': 8, 'R': 0, 'N': 1, 'D': 0, 'C': 0, 'Q': 2, 'E': 0, 'G': 4, 'H': 1, 'I': 1, AC 'L': 5, 'K': 3, 'M': 2, 'F': 1, 'P': 0, 'S': 1, 'T': 4, 'W': 1, 'Y': 0, 'V': 0 AF 'A': 23.53%, 'R': 0%, 'N': 2.94%, 'D': 0%, 'C': 0%, 'Q': 5.88%, 'E': 0%, 'G': 11.76%, 'H': 2.94%, 'I': 2.94%, AF 'L': 14.71%, 'K': 8.82%, 'M': 5.88%, 'F': 2.94%, 'P': 0%, 'S': 2.94%, 'T': 11.76%, 'W': 2.94%, 'Y': 0%, 'V': 0% MA C, D, E, P, R, V, Y MO A LO F, H, I, N, S, W BA 22 LA 12 AA 4 BC 0 MC 0 MF 0 XX MM 3473.112 AI 92.353 II 6.268 HP 0.382 HM 0.459 IP 11.103 C7 3.088 SF 0.235, 0.176, 0.441 [Helix, Turn, Sheet] AR 0.059 ME 5500, 5500 XX TO No Target Organism Found AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Fungicide AM Anti-protozoal EA Not found IE Not found OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 8306981 XR PubMed: 18644413 XR UniProt: P80278 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P80278 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR022731 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 3473.112 DA MW 34AA ALWFTMLKKL GTMALHAGKA ALGAAANTIS QGTQ // ID AMPDB_34923 PN Dermaseptin-S5 PF Dermaseptin-S5 GN Not found SO Phyllomedusa sauvagei (Sauvage`s leaf frog) PL 29 PE Evidence at protein level XX AC 'A': 9, 'R': 0, 'N': 1, 'D': 0, 'C': 0, 'Q': 0, 'E': 0, 'G': 2, 'H': 0, 'I': 1, AC 'L': 1, 'K': 6, 'M': 0, 'F': 0, 'P': 0, 'S': 2, 'T': 2, 'W': 1, 'Y': 0, 'V': 4 AF 'A': 31.03%, 'R': 0%, 'N': 3.45%, 'D': 0%, 'C': 0%, 'Q': 0%, 'E': 0%, 'G': 6.9%, 'H': 0%, 'I': 3.45%, AF 'L': 3.45%, 'K': 20.69%, 'M': 0%, 'F': 0%, 'P': 0%, 'S': 6.9%, 'T': 6.9%, 'W': 3.45%, 'Y': 0%, 'V': 13.79% MA C, D, E, F, H, M, P, Q, R, Y MO A LO I, L, N, W BA 18 LA 11 AA 6 BC 0 MC 0 MF 0 XX MM 2840.406 AI 97.931 II -0.066 HP 0.334 HM 0.632 IP 11.5 C7 5.996 SF 0.241, 0.172, 0.345 [Helix, Turn, Sheet] AR 0.034 ME 5500, 5500 XX TO No Target Organism Found AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Fungicide AM Anti-protozoal EA Not found IE Not found OE Non-hemolytic OE Non-ribosomal XX XR PubMed: 8306981 XR PubMed: 18644413 XR UniProt: P80281 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P80281 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 2840.406 DA MW 29AA GLWSKIKTAG KSVAKAAAKA AVKAVTNAV // ID AMPDB_35178 PN Dermaseptin III-like peptide PF Dermaseptin III-like peptide GN Not found SO Phyllomedusa burmeisteri (Brazilian common walking leaf frog) PL 23 PE Evidence at protein level XX AC 'A': 5, 'R': 0, 'N': 1, 'D': 0, 'C': 0, 'Q': 0, 'E': 0, 'G': 4, 'H': 0, 'I': 1, AC 'L': 4, 'K': 5, 'M': 1, 'F': 0, 'P': 0, 'S': 0, 'T': 0, 'W': 1, 'Y': 0, 'V': 1 AF 'A': 21.74%, 'R': 0%, 'N': 4.35%, 'D': 0%, 'C': 0%, 'Q': 0%, 'E': 0%, 'G': 17.39%, 'H': 0%, 'I': 4.35%, AF 'L': 17.39%, 'K': 21.74%, 'M': 4.35%, 'F': 0%, 'P': 0%, 'S': 0%, 'T': 0%, 'W': 4.35%, 'Y': 0%, 'V': 4.35% MA C, D, E, F, H, P, Q, R, S, T, Y MO A; K LO I, M, N, V, W BA 17 LA 6 AA 5 BC 0 MC 0 MF 0 XX MM 2338.927 AI 119.13 II -7.23 HP 0.404 HM 0.704 IP 11.403 C7 4.997 SF 0.304, 0.217, 0.435 [Helix, Turn, Sheet] AR 0.043 ME 5500, 5500 XX TO No Target Organism Found AM Amphibian defense peptide AM Antibiotic AM Antimicrobial AM Anti-protozoal EA Not found IE Not found OE Non-hemolytic OE Non-ribosomal XX XR PubMed: XR UniProt: P86281 XR RCSB PDB;PDBsum;PDBe;PDBj;PDBe-KB;MMDB: | Method: | Resolution: XR AlphaFoldDB: P86281 XR GenBank;EMBL: XR CCDS: XR RefSeq: XR STRING: XR IntAct: XR MINT: XR DIP: XR BioGRID: XR BindingDB: XR DrugBank: XR ChEMBL: XR InterPro: IPR022731 XR PANTHER: XR PROSITE: XR Ensembl: XR KEGG: XR GeneTree: XR BRENDA: XR BioCyc: XR RNAct: SQ SEQUENCE 2338.927 DA MW 23AA ALWKNMLKGI GKLAGKAALG AVK //